Alexandra L. Sacharok, Ph.D.

Technology Specialist

Overview

Alex applies her background in cell and molecular biology and microbiology to assist clients in the drafting and prosecution of patent applications.

In her doctoral work, Alex studied the pediatric pathogen Kingella kingae, which colonizes the upper respiratory tract in young children and can become invasive, causing bone and joint infections. Her work focused on elucidating the molecular mechanisms of bacterial adherence to host cells. Specifically, she characterized the roles of two type IV pilus-associated proteins, PilC1 and PilC2, in bacterial adherence, twitching motility, and natural competence, identifying the adhesive regions of the proteins responsible for K. kingae adherence to host epithelial cells. This work allowed Alex to develop broad expertise in the areas of microbiology, cell and molecular biology, and protein purification.

Alex has co-authored original research articles in the peer-reviewed journals PLoS Pathogens and Infection and Immunity, and a bacteriology textbook chapter in Principles and Practice of Pediatric Infectious Diseases, 6th Edition.

Education

Ph.D., Cell and Molecular Biology, University of Pennsylvania

B.S., Biochemistry and Molecular Biology, Pennsylvania State University

Experience

Affiliations:

  • American Society for Microbiology

Education

Ph.D., Cell and Molecular Biology, University of Pennsylvania

B.S., Biochemistry and Molecular Biology, Pennsylvania State University