Maria A. DeCicco RePass, Ph.D.

Technology Specialist

Overview

Maria applies significant experience in molecular biochemistry, parasitology, and immunology to help clients develop strategic patent portfolios. She works with a wide range of clients, from academic and research institutions to early-stage and established biotechnology and pharmaceutical companies, on the drafting and prosecution of patent applications. She also assists with IP due diligence through the evaluation of client and competitor portfolios.

An accomplished scientist, Maria’s doctoral research focused on understanding Cryptosporidium-host cell interactions, specifically the role of O-glycosylation during infection. She has also previously investigated the immunological pathways of sterile inflammation. Her studies in host-pathogen interactions, 3D culture model systems, enzymatic characterization, immunology, and downstream in-vitro and in-vivo analyses equip her with technical expertise in cell culture and various other molecular biology techniques, including cloning and recombinant protein expression systems, immunoassays, and in-vivo and in-vitro imaging.

As part of her research studies, Maria:

  • Developed a novel bioengineered 3D human intestinal model to support long-term infection with Cryptosporidium to better characterize the host-parasite interactions.
  • Cloned and enzymatically characterized recombinant polypeptide GalNAc Transferase-4 from parvum to evaluate its potential as a novel therapeutic agent.
  • Identified the principal players responsible for mediating the sterile inflammatory response to acute radiodermatitis in mice, and explored immunomodulation as a therapeutic intervention.

Maria has co-authored original research articles in peer-reviewed journals, including Infection and Immunity, Molecular and Biochemical Parasitology, and Radiation Research; additional publications are forthcoming.

Education

Ph.D., Immunology, Tufts University Sackler School of Graduate Biomedical Sciences

B.S. with high distinction, Biochemistry, Worcester Polytechnic Institute

Experience

Honors:

  • Future of Science Award, Keystone Symposia
  • Lalor Travel Award, Tufts University Immunology Program

Affiliations:

  • Volunteer Judge, Massachusetts State High School Science and Engineering Fair

Education

Ph.D., Immunology, Tufts University Sackler School of Graduate Biomedical Sciences

B.S. with high distinction, Biochemistry, Worcester Polytechnic Institute